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APEX1 promotes the oncogenicity of hepatocellular carcinoma via regulation of MAP2K6

Objective: Apurinic/apyrimidinic endonuclease 1 (APEX1), a key enzyme responsible for DNA base excision repair, has been linked to development and progression of cancers. In this work, we aimed to explore the role of APEX1 in hepatocellular carcinoma (HCC) and elucidate its molecular mechanism. Meth...

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Detalles Bibliográficos
Autores principales: Sun, Zhipeng, Chen, Guangyang, Wang, Liang, Sang, Qing, Xu, Guangzhong, Zhang, Nengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596212/
https://www.ncbi.nlm.nih.gov/pubmed/36205565
http://dx.doi.org/10.18632/aging.204325