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Comprehensive bioinformatics analysis of ribonucleoside diphosphate reductase subunit M2(RRM2) gene correlates with prognosis and tumor immunotherapy in pan-cancer

Ribonucleotide reductase (RNR) small subunit M2 (RRM2) levels are known to regulate the activity of RNR, a rate-limiting enzyme in the synthesis of deoxyribonucleotide triphosphates (dNTPs) and essential for both DNA replication and repair. The high expression of RRM2 enhances the proliferation of c...

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Detalles Bibliográficos
Autores principales: Wu, Liyuan, Yin, Le, Ma, Linxiang, Yang, Jiarui, Yang, Feiya, Sun, Baofa, Nianzeng, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596216/
https://www.ncbi.nlm.nih.gov/pubmed/36202136
http://dx.doi.org/10.18632/aging.204315