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Novel small molecular compound 2JY-OBZ4 alleviates AD pathology in cell models via regulating multiple targets

Alzheimer’s disease (AD) is the most common form of neurodegenerative dementia, characterized by cognitive deficits and memory dysfunction, which is clinically incurable so far. Novel small molecular compound 2JY-OBZ4 is one of structural analogue of Huperzine A (Hup-A), an anti-AD drug in China. In...

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Detalles Bibliográficos
Autores principales: Guo, Qian, Wu, Gang, Huang, Fang, Wei, Zhen, Wang, Jian-Zhi, Zhang, Bin, Liu, Rong, Yang, Yang, Wang, Xiaochuan, Li, Hong-Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596221/
https://www.ncbi.nlm.nih.gov/pubmed/36227154
http://dx.doi.org/10.18632/aging.204336