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Natural variation in macrophage polarization and function impact pneumocyte senescence and susceptibility to fibrosis

Radiation-induced pulmonary fibrosis (RIPF), a late adverse event of radiation therapy, is characterized by infiltration of inflammatory cells, progressive loss of alveolar structure, secondary to the loss of pneumocytes and accumulation of collagenous extracellular matrix, and senescence of alveola...

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Detalles Bibliográficos
Autores principales: Chung, Eun Joo, Kwon, Seokjoo, Shankavaram, Uma, White, Ayla O., Das, Shaoli, Citrin, Deborah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596223/
https://www.ncbi.nlm.nih.gov/pubmed/36173617
http://dx.doi.org/10.18632/aging.204309