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Long Noncoding RNA XIST Promotes Resistance to Lenvatinib in Hepatocellular Carcinoma Cells via Epigenetic Inhibition of NOD2

Background. Hepatocellular carcinoma (HCC) is a severe global health issue that still lacks of effective treatments. Lenvatinib is a novel tyrosine kinase inhibitor (TKI) that has been approved for the treatment of HCC. However, drug resistance is inevitable and limits the clinical application of le...

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Detalles Bibliográficos
Autores principales: Duan, Anqi, Li, Hui, Yu, Wenlong, Zhang, Yongjie, Yin, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596241/
https://www.ncbi.nlm.nih.gov/pubmed/36304988
http://dx.doi.org/10.1155/2022/4537343