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Association of artificial intelligence-powered and manual quantification of programmed death-ligand 1 (PD-L1) expression with outcomes in patients treated with nivolumab ± ipilimumab

Assessment of programmed death ligand 1 (PD-L1) expression by immunohistochemistry (IHC) has emerged as an important predictive biomarker across multiple tumor types. However, manual quantitation of PD-L1 positivity can be difficult and leads to substantial inter-observer variability. Although the d...

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Detalles Bibliográficos
Autores principales: Baxi, Vipul, Lee, George, Duan, Chunzhe, Pandya, Dimple, Cohen, Daniel N., Edwards, Robin, Chang, Han, Li, Jun, Elliott, Hunter, Pokkalla, Harsha, Glass, Benjamin, Agrawal, Nishant, Lahiri, Abhik, Wang, Dayong, Khosla, Aditya, Wapinski, Ilan, Beck, Andrew, Montalto, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596372/
https://www.ncbi.nlm.nih.gov/pubmed/35840720
http://dx.doi.org/10.1038/s41379-022-01119-2