Cargando…

An RNA aptamer that shifts the reduction potential of metabolic cofactors

The discovery of ribozymes has inspired exploration of RNA’s potential to serve as primordial catalysts in a hypothesized RNA world. Modern oxidoreductase enzymes employ differential binding between reduced and oxidized forms of redox cofactors to alter cofactor reduction potential and enhance the e...

Descripción completa

Detalles Bibliográficos
Autores principales: Samuelian, John S., Gremminger, Thomas J., Song, Zhenwei, Poudyal, Raghav R., Li, Jun, Zhou, Yuanzhe, Staller, Seth A., Carballo, Johan A., Roychowdhury-Saha, Manami, Chen, Shi-Jie, Burke, Donald H., Heng, Xiao, Baum, Dana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596375/
https://www.ncbi.nlm.nih.gov/pubmed/36097297
http://dx.doi.org/10.1038/s41589-022-01121-4