The SUMO protease SENP1 promotes aggressive behaviors of high HIF2α expressing renal cell carcinoma cells

While an important role for the SUMO protease SENP1 is recognized in multiple solid cancers, its role in renal cell carcinoma (RCC) pathogenesis, particularly the most dominant subtype, clear cell RCC (ccRCC), is poorly understood. Here we show that a combination of high HIF2α and SENP1 expression i...

Descripción completa

Detalles Bibliográficos
Autores principales: Lee, Moon Hee, Sung, Kyung, Beebe, David, Huang, Wei, Shapiro, Dan, Miyamoto, Shigeki, Abel, E. Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596416/
https://www.ncbi.nlm.nih.gov/pubmed/36284084
http://dx.doi.org/10.1038/s41389-022-00440-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596416/
https://www.ncbi.nlm.nih.gov/pubmed/36284084
http://dx.doi.org/10.1038/s41389-022-00440-4

Ejemplares similares