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Glial cell reactivity and oxidative stress prevention in Alzheimer’s disease mice model by an optimized NMDA receptor antagonist

In Alzheimer's disease pathology, several neuronal processes are dysregulated by excitotoxicity including neuroinflammation and oxidative stress (OS). New therapeutic agents capable of modulating such processes are needed to foster neuroprotection. Here, the effect of an optimised NMDA receptor...

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Detalles Bibliográficos
Autores principales: Companys-Alemany, Júlia, Turcu, Andreea L., Vázquez, Santiago, Pallàs, Mercè, Griñán-Ferré, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596444/
https://www.ncbi.nlm.nih.gov/pubmed/36284170
http://dx.doi.org/10.1038/s41598-022-22963-x