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A novel metagenome-derived viral RNA polymerase and its application in a cell-free expression system for metagenome screening

The mining of genomes from non-cultivated microorganisms using metagenomics is a powerful tool to discover novel proteins and other valuable biomolecules. However, function-based metagenome searches are often limited by the time-consuming expression of the active proteins in various heterologous hos...

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Detalles Bibliográficos
Autores principales: Han, Yuchen, Kinfu, Birhanu M., Blombach, Fabian, Cackett, Gwenny, Zhang, Hongli, Pérez-García, Pablo, Krohn, Ines, Salomon, Jesper, Besirlioglu, Volkan, Mirzaeigarakani, Tayebeh, Schwaneberg, Ulrich, Chow, Jennifer, Werner, Finn, Streit, Wolfgang R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596486/
https://www.ncbi.nlm.nih.gov/pubmed/36284144
http://dx.doi.org/10.1038/s41598-022-22383-x