Integrative tumour mutation burden with CD39 and PD-L1 for the prediction of response to PD-L1 blockade and adjuvant chemotherapy in muscle-invasive bladder cancer patients

BACKGROUND: CD39, a rate-limiting enzyme to convert extracellular ATP (eATP) to adenosine, has been reported to be a key modulator of immune response, but its correlation with therapeutic sensitivity remains obscure. We conducted this study to determine whether the integration of CD39 and traditiona...

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Detalles Bibliográficos
Autores principales: Liu, Chunnan, Liu, Zhaopei, Jin, Kaifeng, Zeng, Han, Shao, Fei, Chang, Yuan, Wang, Yiwei, Xu, Le, Wang, Zewei, Zhu, Yu, Zhang, Weijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596489/
https://www.ncbi.nlm.nih.gov/pubmed/35999267
http://dx.doi.org/10.1038/s41416-022-01943-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596489/
https://www.ncbi.nlm.nih.gov/pubmed/35999267
http://dx.doi.org/10.1038/s41416-022-01943-y

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