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Loss of thyroid gland circadian PER2 rhythmicity in aged mice and its potential association with thyroid cancer development
Molecular clocks operate in peripheral tissues, including endocrine glands, and play important regulatory roles in this context. However, potential age-related changes in the expression rhythmicity of clock genes and the effects of these changes on the thyroid gland remain unknown. In the present st...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596494/ https://www.ncbi.nlm.nih.gov/pubmed/36284088 http://dx.doi.org/10.1038/s41419-022-05342-2 |