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BRAF Inhibitor Resistance in Melanoma: Mechanisms and Alternative Therapeutic Strategies
Melanoma is caused by a variety of somatic mutations, and among these mutations, BRAF mutation occurs most frequently and has routinely been evaluated as a critical diagnostic biomarker in clinical practice. The introduction of targeted agents for BRAF-mutant melanoma has significantly improved over...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596525/ https://www.ncbi.nlm.nih.gov/pubmed/36181568 http://dx.doi.org/10.1007/s11864-022-01006-7 |