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Epigenetic regulation of pancreatic adenocarcinoma in the era of cancer immunotherapy

Pancreatic adenocarcinoma is a lethal cancer with poor response to chemotherapy and immune checkpoint inhibitors. Recent studies suggest that epigenetic alterations contribute to its aggressive biology and the tumor microenvironment which render it unresponsive to immune checkpoint blockade. Here, w...

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Detalles Bibliográficos
Autores principales: Kawakubo, Kazumichi, Castillo, Carlos Fernandez-del, Liss, Andrew Scott
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596544/
https://www.ncbi.nlm.nih.gov/pubmed/36048239
http://dx.doi.org/10.1007/s00535-022-01915-2