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Epigenetic regulation of pancreatic adenocarcinoma in the era of cancer immunotherapy
Pancreatic adenocarcinoma is a lethal cancer with poor response to chemotherapy and immune checkpoint inhibitors. Recent studies suggest that epigenetic alterations contribute to its aggressive biology and the tumor microenvironment which render it unresponsive to immune checkpoint blockade. Here, w...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Nature Singapore
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596544/ https://www.ncbi.nlm.nih.gov/pubmed/36048239 http://dx.doi.org/10.1007/s00535-022-01915-2 |