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Diffusive drug delivery in the brain extracellular space from a cellular scale microtube
The effectiveness of state-of-the-art systemic treatments for neurological disorders is hampered not only by the difficulty in crossing the blood brain barrier but also off-target drug interactions. In this study, a delivery method is simulated for a novel U-shaped microtube locally infusing drugs d...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596563/ https://www.ncbi.nlm.nih.gov/pubmed/36312901 http://dx.doi.org/10.1557/s43579-022-00247-9 |