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Epigenetic inactivation of DNA repair genes as promising prognostic and predictive biomarkers in urothelial bladder carcinoma patients

We sought to examine epigenetic inactivation of DNA damage repair (DDR) genes as prognostic and predictive biomarkers for urothelial bladder cancer (UBC) as there are currently no reliable prognostic biomarkers that identify UBC patients who would benefit from chemotherapy. Genome-wide DNA methylome...

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Detalles Bibliográficos
Autores principales: Mohanad, Marwa, Yousef, Hend F., Bahnassy, Abeer A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596572/
https://www.ncbi.nlm.nih.gov/pubmed/36076047
http://dx.doi.org/10.1007/s00438-022-01950-x