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Inhibition of Rho/ROCK signaling pathway participates in the cardiac protection of exercise training in spontaneously hypertensive rats

Exercise training (ExT) is capable of improving the heart function of spontaneously hypertensive rats (SHRs), but the underlying molecular mechanisms remain elusive. This study was aimed to investigate whether inhibition of RhoA/ROCK signaling pathway contributes to the cardiac protection by low-int...

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Detalles Bibliográficos
Autores principales: Li, Mengwei, Zhang, Limei, Liu, Xinyan, Wang, Guoqiang, Lu, Jian, Guo, Jifeng, Wang, Hongjie, Xu, Jinpeng, Zhang, Yi, Li, Na, Zhou, You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596711/
https://www.ncbi.nlm.nih.gov/pubmed/36284153
http://dx.doi.org/10.1038/s41598-022-22191-3