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Ferrostatin-1 alleviates tissue and cell damage in diabetic retinopathy by improving the antioxidant capacity of the Xc(-)-GPX4 system

Diabetic retinopathy (DR) is a common microvascular complication leading to a high blindness rate among patients with diabetes. Ferroptosis is a type of cell death caused by the accumulation of iron-dependent lipid peroxides. Studies have shown that ferroptosis plays an important role in DR. The rat...

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Detalles Bibliográficos
Autores principales: Shao, Jingzhi, Bai, Zhouxian, Zhang, Lirong, Zhang, Fengyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596714/
https://www.ncbi.nlm.nih.gov/pubmed/36284090
http://dx.doi.org/10.1038/s41420-022-01141-y