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Lcn2 mediates adipocyte-muscle-tumor communication and hypothermia in pancreatic cancer cachexia

OBJECTIVE: Adipose tissue is the largest endocrine organ. When activated by cancer cells, adipocytes secrete adipocytokines and release fatty acids, which are then transferred to cancer cells and used for structural and biochemical support. How this metabolic symbiosis between cancer cells and adipo...

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Detalles Bibliográficos
Autores principales: Lemecha, Mengistu, Chalise, Jaya Prakash, Takamuku, Yuki, Zhang, Guoxiang, Yamakawa, Takahiro, Larson, Garrett, Itakura, Keiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596731/
https://www.ncbi.nlm.nih.gov/pubmed/36243318
http://dx.doi.org/10.1016/j.molmet.2022.101612