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Lcn2 mediates adipocyte-muscle-tumor communication and hypothermia in pancreatic cancer cachexia
OBJECTIVE: Adipose tissue is the largest endocrine organ. When activated by cancer cells, adipocytes secrete adipocytokines and release fatty acids, which are then transferred to cancer cells and used for structural and biochemical support. How this metabolic symbiosis between cancer cells and adipo...
Autores principales: | Lemecha, Mengistu, Chalise, Jaya Prakash, Takamuku, Yuki, Zhang, Guoxiang, Yamakawa, Takahiro, Larson, Garrett, Itakura, Keiichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596731/ https://www.ncbi.nlm.nih.gov/pubmed/36243318 http://dx.doi.org/10.1016/j.molmet.2022.101612 |
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