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Investigation of anti-diabetic potential and molecular simulation studies of dihydropyrimidinone derivatives

In an attempt to find new targets for α-amylase and α-glucosidase for the treatment of type 2 diabetes mellitus, the present study aims in determining the anti-diabetic potential of synthesized dihydropyrimidinone derivatives. The in vitro α-glucosidase and α-amylase inhibitory activity was performe...

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Detalles Bibliográficos
Autores principales: Ilyas, Umair, Nazir, Bisma, Altaf, Reem, Muhammad, Syed Aun, Zafar, Hajra, Paiva-Santos, Ana Cláudia, Abbas, Muhammad, Duan, Yongtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596752/
https://www.ncbi.nlm.nih.gov/pubmed/36313779
http://dx.doi.org/10.3389/fendo.2022.1022623