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Identification of hub genes and their correlation with infiltration of immune cells in MYCN positive neuroblastoma based on WGCNA and LASSO algorithm

BACKGROUND: The prognosis of MYCN positive NB is poor, and there is no targeted drug for N-myc at present. This study aims to screen out hub genes closely related to MYCN, analyze the relationship between hub genes and NB microenvironment, and provide basis for molecular targeted therapy of MYCN pos...

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Detalles Bibliográficos
Autores principales: Chen, Ji, Sun, Mengjiao, Chen, Chuqin, Jiang, Bin, Fang, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596756/
https://www.ncbi.nlm.nih.gov/pubmed/36311753
http://dx.doi.org/10.3389/fimmu.2022.1016683