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Identification of hub genes and their correlation with infiltration of immune cells in MYCN positive neuroblastoma based on WGCNA and LASSO algorithm
BACKGROUND: The prognosis of MYCN positive NB is poor, and there is no targeted drug for N-myc at present. This study aims to screen out hub genes closely related to MYCN, analyze the relationship between hub genes and NB microenvironment, and provide basis for molecular targeted therapy of MYCN pos...
Autores principales: | Chen, Ji, Sun, Mengjiao, Chen, Chuqin, Jiang, Bin, Fang, Yongjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596756/ https://www.ncbi.nlm.nih.gov/pubmed/36311753 http://dx.doi.org/10.3389/fimmu.2022.1016683 |
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