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HKI-272 contributes to gemcitabine-mediated anti-proliferative and anti-metastatic effects through EGFR suppression in gallbladder cancer

Gallbladder cancer (GBC) is a rare malignancy of the biliary system and characterized by early metastasis and poor prognosis. To date, no efficient treatment is available for GBC patients. Based on the data from cBioPortal, TIMER, and GDSC, we performed an unbiased screening with 25 candidate compou...

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Detalles Bibliográficos
Autores principales: Yang, Xuli, Chen, Tao, Hu, Jie, Wang, Jian, Yang, Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596964/
https://www.ncbi.nlm.nih.gov/pubmed/36321135
http://dx.doi.org/10.1016/j.omto.2022.10.004