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Assessment of (99m)Tc-NTP 15-5 uptake on cartilage, a new proteoglycan tracer: Study protocol for a phase I trial (CARSPECT)

BACKGROUND: (99m)Tc-NTP 15-5 is a SPECT radiotracer targeting proteoglycans (PG), components of the cartilaginous extracellular matrix. Imaging of PGs would be useful for the early detection of cartilage disorders (osteoarthritis, arthritis and chondrosarcoma, Aromatase Inhibitor associated arthralg...

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Detalles Bibliográficos
Autores principales: Thivat, Emilie, Chanchou, Marion, Mathieu, Sylvain, Levesque, Sophie, Billoux, Tommy, Auzeloux, Philippe, Sas, Nicolas, Molnar, Ioana, Jouberton, Elodie, Rouanet, Jacques, Fois, Giovanna, Maigne, Lydia, Galmier, Marie-Josephe, Penault-Llorca, Frédérique, Miot-Noirault, Elisabeth, Durando, Xavier, Cachin, Florent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9596979/
https://www.ncbi.nlm.nih.gov/pubmed/36314021
http://dx.doi.org/10.3389/fmed.2022.993151