Hoxa9/meis1-transgenic zebrafish develops acute myeloid leukaemia-like disease with rapid onset and high penetrance

HOXA9 and MEIS1 are co-expressed in over 50% of acute myeloid leukaemia (AML) and play essential roles in leukaemogenesis, but the mechanisms involved are poorly understood. Diverse animal models offer valuable tools to recapitulate different aspects of AML and link in vitro studies to clinical tria...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Li, Hongji, Huang, Mengling, Wang, Xue, Li, Wei, Qian, Xiaoqing, Jing, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597180/
https://www.ncbi.nlm.nih.gov/pubmed/36285442
http://dx.doi.org/10.1098/rsob.220172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597180/
https://www.ncbi.nlm.nih.gov/pubmed/36285442
http://dx.doi.org/10.1098/rsob.220172

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