Auranofin attenuates hepatic steatosis and fibrosis in nonalcoholic fatty liver disease via NRF2 and NF-κB signaling pathways

BACKGROUND/AIMS: We aim to evaluate the effects of auranofin, a known antioxidant, on hepatic steatosis, inflammation, and fibrosis, contributing to non-alcoholic steatohepatitis (NASH) development in vivo and in vitro. METHODS: Transcriptome analysis of LX-2 cells was that expression patterns of ge...

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Detalles Bibliográficos
Autores principales: Lee, Seung Min, Koh, Dong Hee, Jun, Dae Won, Roh, Yoon Jin, Kang, Hyeon Tae, Oh, Ju Hee, Kim, Hyun Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association for the Study of the Liver 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597229/
https://www.ncbi.nlm.nih.gov/pubmed/35730208
http://dx.doi.org/10.3350/cmh.2022.0068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597229/
https://www.ncbi.nlm.nih.gov/pubmed/35730208
http://dx.doi.org/10.3350/cmh.2022.0068

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