Preclinical reserpine models recapitulating motor and non-motor features of Parkinson’s disease: Roles of epigenetic upregulation of alpha-synuclein and autophagy impairment

Reserpine is an effective drug for the clinical treatment of hypertension. It also induces Parkinson’s disease (PD)-like symptoms in humans and animals possible through the inhibition of monoamine vesicular transporters, thus decreasing the levels of monoamine neurotransmitters in the brain. However...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Yang, Yin, Qiao, Wang, Bing, Shen, Tingting, Luo, Weifeng, Liu, Tong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597253/
https://www.ncbi.nlm.nih.gov/pubmed/36313295
http://dx.doi.org/10.3389/fphar.2022.944376

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597253/
https://www.ncbi.nlm.nih.gov/pubmed/36313295
http://dx.doi.org/10.3389/fphar.2022.944376

Ejemplares similares