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Preclinical reserpine models recapitulating motor and non-motor features of Parkinson’s disease: Roles of epigenetic upregulation of alpha-synuclein and autophagy impairment

Reserpine is an effective drug for the clinical treatment of hypertension. It also induces Parkinson’s disease (PD)-like symptoms in humans and animals possible through the inhibition of monoamine vesicular transporters, thus decreasing the levels of monoamine neurotransmitters in the brain. However...

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Detalles Bibliográficos
Autores principales:	Li, Yang, Yin, Qiao, Wang, Bing, Shen, Tingting, Luo, Weifeng, Liu, Tong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597253/ https://www.ncbi.nlm.nih.gov/pubmed/36313295 http://dx.doi.org/10.3389/fphar.2022.944376

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