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Multi-trial analysis of HIV-1 envelope gp41-reactive antibodies among global recipients of candidate HIV-1 vaccines

Many participants in HIV-1 vaccine trials, who have not previously been exposed to or vaccinated against HIV-1, display serum immunoglobulin antibodies that bind the gp41 region of HIV-1 envelope prior to vaccination. Previous studies have hypothesized that these pre-existing antibodies may be cross...

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Detalles Bibliográficos
Autores principales: Mayer-Blackwell, Koshlan, Johnson, Andrew M., Potchen, Nicole, Minot, Simon S., Heptinstall, Jack, Seaton, Kelly, Sawant, Sheetal, Shen, Xiaoying, Tomaras, Georgia D., Fiore-Gartland, Andrew, Kublin, James G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597301/
https://www.ncbi.nlm.nih.gov/pubmed/36311720
http://dx.doi.org/10.3389/fimmu.2022.983313