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Transcriptional dynamics of pluripotent stem cell-derived endothelial cell differentiation revealed by single-cell RNA sequencing

AIMS: Pluripotent stem cell-derived endothelial cell products possess therapeutic potential in ischaemic vascular disease. However, the factors that drive endothelial differentiation from pluripotency and cellular specification are largely unknown. The aims of this study were to use single-cell RNA...

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Detalles Bibliográficos
Autores principales: McCracken, Ian R, Taylor, Richard S, Kok, Fatma O, de la Cuesta, Fernando, Dobie, Ross, Henderson, Beth E P, Mountford, Joanne C, Caudrillier, Axelle, Henderson, Neil C, Ponting, Chris P, Baker, Andrew H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597329/
https://www.ncbi.nlm.nih.gov/pubmed/31242503
http://dx.doi.org/10.1093/eurheartj/ehz351