RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes

Arl8b, an Arf-like GTP-binding protein, regulates cargo trafficking and positioning of lysosomes. However, it is unknown whether Arl8b regulates lysosomal cargo sorting. Here, we report that Arl8b binds to the Rab4 and Rab14 interaction partner, RUN and FYVE domain-containing protein (RUFY) 1, a kno...

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Detalles Bibliográficos
Autores principales: Rawat, Shalini, Chatterjee, Dhruba, Marwaha, Rituraj, Charak, Gitanjali, Kumar, Gaurav, Shaw, Shrestha, Khatter, Divya, Sharma, Sheetal, de Heus, Cecilia, Liv, Nalan, Klumperman, Judith, Tuli, Amit, Sharma, Mahak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597352/
https://www.ncbi.nlm.nih.gov/pubmed/36282215
http://dx.doi.org/10.1083/jcb.202108001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597352/
https://www.ncbi.nlm.nih.gov/pubmed/36282215
http://dx.doi.org/10.1083/jcb.202108001

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