kinCSM: Using graph‐based signatures to predict small molecule CDK2 inhibitors

Protein phosphorylation acts as an essential on/off switch in many cellular signaling pathways. This has led to ongoing interest in targeting kinases for therapeutic intervention. Computer‐aided drug discovery has been proven a useful and cost‐effective approach for facilitating prioritization and e...

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Detalles Bibliográficos
Autores principales: Zhou, Yunzhuo, Al‐Jarf, Raghad, Alavi, Azadeh, Nguyen, Thanh Binh, Rodrigues, Carlos H. M., Pires, Douglas E. V., Ascher, David B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2022
Materias:
Tools for Protein Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597374/
https://www.ncbi.nlm.nih.gov/pubmed/36305769
http://dx.doi.org/10.1002/pro.4453

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597374/
https://www.ncbi.nlm.nih.gov/pubmed/36305769
http://dx.doi.org/10.1002/pro.4453

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