Dexamethasone and potassium canrenoate alleviate hyperalgesia by competitively regulating IL‐6/JAK2/STAT3 signaling pathway during inflammatory pain in vivo and in vitro

BACKGROUND: Dexamethasone (Dexa) and potassium canrenoate (Cane) modulate nociceptive behavior via glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) by two mechanisms (genomic and nongenomic pathways). This study was designed to investigate the Dexa‐ or Cane‐mediated nongenomic and ge...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Xie, Xiaolan, Qin, Kai, Xu, Le, Peng, Juxiang, Li, Xiangyu, Li, Xiongjuan, Liu, Zhiheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597488/
https://www.ncbi.nlm.nih.gov/pubmed/36301041
http://dx.doi.org/10.1002/iid3.721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597488/
https://www.ncbi.nlm.nih.gov/pubmed/36301041
http://dx.doi.org/10.1002/iid3.721

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