SNS-032 attenuates liver fibrosis by anti-active hepatic stellate cells via inhibition of cyclin dependent kinase 9

Liver fibrosis is a common pathological process of all chronic liver diseases. Hepatic stellate cells (HSCs) play a central role in the development of liver fibrosis. Cyclin-dependent kinase 9 (CDK9) is a cell cycle kinase that regulates mRNA transcription and elongation. A CDK9 inhibitor SNS-032 ha...

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Detalles Bibliográficos
Autores principales: He, Xiao-Li, Hu, Yong-Hong, Chen, Jia-Mei, Zhang, Ding-Qi, Yang, Hai-Lin, Zhang, Lin-Zhang, Mu, Yong-Ping, Zhang, Hua, Chen, Gao-Feng, Liu, Wei, Liu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597511/
https://www.ncbi.nlm.nih.gov/pubmed/36313366
http://dx.doi.org/10.3389/fphar.2022.1016552

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597511/
https://www.ncbi.nlm.nih.gov/pubmed/36313366
http://dx.doi.org/10.3389/fphar.2022.1016552

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