Intranasal SARS-CoV-2 spike-based immunisation adjuvanted with polyethyleneimine elicits mucosal and systemic humoral responses in mice

The SARS-CoV-2 pandemic continues despite the presence of effective vaccines, and novel vaccine approaches may help to reduce viral spread and associated COVID-19 disease. Current vaccine administration modalities are based on systemic needle-administered immunisation which may be suboptimal for muc...

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Detalles Bibliográficos
Autores principales: Deimel, Lachlan P., Liu, Xin, Gilbert-Jaramillo, Javier, Liu, Sai, James, William S., Sattentau, Quentin J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier B.V. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597555/
https://www.ncbi.nlm.nih.gov/pubmed/36306825
http://dx.doi.org/10.1016/j.jim.2022.113380

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597555/
https://www.ncbi.nlm.nih.gov/pubmed/36306825
http://dx.doi.org/10.1016/j.jim.2022.113380

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