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Genetic regulation of iron homeostasis in sideropenic patients with mild COVID-19 disease under a new oral iron formulation: Lessons from a different perspective

BACKGROUND: Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) needs iron to replicate itself. Coronaviruses are able to upregulate Chop/Gadd153 and Arg1 genes, consequently leading to CD8 lymphocytes decrease, degradation of asparagine and decreased nitric oxide (NO), thus impairing immun...

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Detalles Bibliográficos
Autores principales: Giordano, Giulio, Bochicchio, Maria Teresa, Niro, Giovanna, Lucchesi, Alessandro, Napolitano, Mariasanta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier GmbH. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597571/
https://www.ncbi.nlm.nih.gov/pubmed/36327544
http://dx.doi.org/10.1016/j.imbio.2022.152297