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Microglial exosomal miR-466i-5p induces brain injury via promoting hippocampal neuron apoptosis in heatstroke

BACKGROUND: Brain injury is the main cause of poor prognosis in heatstroke (HS) patients due to heat-stress-induced neuronal apoptosis. However, as a new cross-talk way among cells, whether microglial exosomal-microRNAs (miRNAs) are involved in HS-induced neuron apoptosis has not been elucidated. ME...

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Detalles Bibliográficos
Autores principales: Zhu, Jie, Chen, Yahong, Ji, Jingjing, Wang, Longyan, Xie, Guoqiang, Tang, Zhen, Qu, Xiangmeng, Liu, Zhifeng, Ren, Guangli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597693/
https://www.ncbi.nlm.nih.gov/pubmed/36311808
http://dx.doi.org/10.3389/fimmu.2022.968520