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One Stone Two Birds: Redox-Sensitive Colocalized Delivery of Cisplatin and Nitric Oxide through Cascade Reactions

[Image: see text] Bio-orthogonal bond-cleavage reactions have been used in cancer therapy for improving the biological specificity of prodrug activation, but the spatiotemporal consistency of reactants is still a huge challenge. Although, in most cases, the cleavage catalysts and caged prodrugs are...

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Detalles Bibliográficos
Autores principales: Wu, Jianbing, Hu, Yihui, Ye, Hui, Zhang, Sheng, Zhu, Jie, Ji, Duorui, Zhang, Yihua, Ding, Ya, Huang, Zhangjian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597859/
https://www.ncbi.nlm.nih.gov/pubmed/36311834
http://dx.doi.org/10.1021/jacsau.2c00390