In vitro effect of Withania somnifera, AYUSH-64, and remdesivir on the activity of CYP-450 enzymes: Implications for possible herb−drug interactions in the management of COVID-19

Ayurvedic medicines Withania somnifera Dunal (ashwagandha) and AYUSH-64 have been used for the prevention and management of COVID-19 in India. The present study explores the effect of Ashwagandha and AYUSH-64 on important human CYP enzymes (CYP3A4, CYP2C8, and CYP2D6) to assess their interaction wit...

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Detalles Bibliográficos
Autores principales: Kasarla, Siva Swapna, Borse, Swapnil P., Kumar, Yashwant, Sharma, Neha, Dikshit, Madhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597875/
https://www.ncbi.nlm.nih.gov/pubmed/36313313
http://dx.doi.org/10.3389/fphar.2022.973768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597875/
https://www.ncbi.nlm.nih.gov/pubmed/36313313
http://dx.doi.org/10.3389/fphar.2022.973768

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