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Intermittent hypoxia enhances the expression of hypoxia inducible factor HIF1A through histone demethylation

The cellular response to hypoxia is regulated through enzymatic oxygen sensors, including the prolyl hydroxylases, which control degradation of the well-known hypoxia inducible factors (HIFs). Other enzymatic oxygen sensors have been recently identified, including members of the KDM histone demethyl...

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Detalles Bibliográficos
Autores principales: Martinez, Chloe-Anne, Jiramongkol, Yannasittha, Bal, Neha, Alwis, Imala, Nedoboy, Polina E., Farnham, Melissa M.J., White, Mark D., Cistulli, Peter A., Cook, Kristina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597902/
https://www.ncbi.nlm.nih.gov/pubmed/36174675
http://dx.doi.org/10.1016/j.jbc.2022.102536