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Combining denoising of RNA-seq data and flux balance analysis for cluster analysis of single cells
BACKGROUND: Sophisticated methods to properly pre-process and analyze the increasing collection of single-cell RNA sequencing (scRNA-seq) data are increasingly being developed. On the contrary, the best practices to integrate these data into metabolic networks, aiming at describing metabolic phenoty...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597960/ https://www.ncbi.nlm.nih.gov/pubmed/36284276 http://dx.doi.org/10.1186/s12859-022-04967-6 |