BoostMEC: predicting CRISPR-Cas9 cleavage efficiency through boosting models

BACKGROUND: In the CRISPR-Cas9 system, the efficiency of genetic modifications has been found to vary depending on the single guide RNA (sgRNA) used. A variety of sgRNA properties have been found to be predictive of CRISPR cleavage efficiency, including the position-specific sequence composition of...

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Detalles Bibliográficos
Autores principales: Zarate, Oscar A., Yang, Yiben, Wang, Xiaozhong, Wang, Ji-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597963/
https://www.ncbi.nlm.nih.gov/pubmed/36289480
http://dx.doi.org/10.1186/s12859-022-04998-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597963/
https://www.ncbi.nlm.nih.gov/pubmed/36289480
http://dx.doi.org/10.1186/s12859-022-04998-z

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