Targeting ERRα promotes cytotoxic effects against acute myeloid leukemia through suppressing mitochondrial oxidative phosphorylation

Acute myeloid leukemia (AML) is an aggressive blood cancer with poor clinical outcomes. Emerging data suggest that mitochondrial oxidative phosphorylation (mtOXPHOS) plays a significant role in AML tumorigenesis, progression, and resistance to chemotherapies. However, how the mtOXPHOS is regulated i...

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Detalles Bibliográficos
Autores principales: Seo, Wonhyoung, Yoo, Seungyeul, Zhong, Yi, Lee, Sang-Hee, Woo, Soo-Yeon, Choi, Hee-Seon, Won, Minho, Roh, Taylor, Jeon, Sang Min, Kim, Kyeong Tae, Silwal, Prashanta, Lee, Min Joung, Heo, Jun Young, Lawlor, Nathan, Kim, Sup, Lee, Dongjun, Kim, Jin-Man, Song, Ik-Chan, Zhu, Jun, Jo, Eun-Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Correspondence
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597966/
https://www.ncbi.nlm.nih.gov/pubmed/36289517
http://dx.doi.org/10.1186/s13045-022-01372-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597966/
https://www.ncbi.nlm.nih.gov/pubmed/36289517
http://dx.doi.org/10.1186/s13045-022-01372-7

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