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Development of a multicellular in vitro model of the meningeal blood-CSF barrier to study Neisseria meningitidis infection

BACKGROUND: Bacterial meningitis is a life-threatening disease that occurs when pathogens such as Neisseria meningitidis cross the meningeal blood cerebrospinal fluid barrier (mBCSFB) and infect the meninges. Due to the human-specific nature of N. meningitidis, previous research investigating this c...

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Detalles Bibliográficos
Autores principales: Endres, Leo M., Jungblut, Marvin, Divyapicigil, Mustafa, Sauer, Markus, Stigloher, Christian, Christodoulides, Myron, Kim, Brandon J., Schubert-Unkmeir, Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9597984/
https://www.ncbi.nlm.nih.gov/pubmed/36289516
http://dx.doi.org/10.1186/s12987-022-00379-z