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Degradome-focused RNA interference screens to identify proteases important for breast cancer cell growth

Proteases are known to promote or impair breast cancer progression and metastasis. However, while a small number of the 588 human and 672 murine protease genes have been extensively studied, others were neglected. For an unbiased functional analysis of all genome-encoded proteases, i.e., the degrado...

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Detalles Bibliográficos
Autores principales: Hölzen, Lena, Syré, Kerstin, Mitschke, Jan, Brummer, Tilman, Miething, Cornelius, Reinheckel, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598039/
https://www.ncbi.nlm.nih.gov/pubmed/36313646
http://dx.doi.org/10.3389/fonc.2022.960109