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Lipid Microenvironment Modulates the Pore-Forming Ability of Polymyxin B

The ability of polymyxin B, an antibiotic used to treat infections caused by multidrug-resistant Gram-negative bacteria as a last-line therapeutic option, to form ion pores in model membranes composed of various phospholipids and lipopolysaccharides was studied. Our data demonstrate that polymyxin B...

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Detalles Bibliográficos
Autores principales: Zakharova, Anastasiia A., Efimova, Svetlana S., Ostroumova, Olga S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598075/
https://www.ncbi.nlm.nih.gov/pubmed/36290103
http://dx.doi.org/10.3390/antibiotics11101445