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Lipid Microenvironment Modulates the Pore-Forming Ability of Polymyxin B
The ability of polymyxin B, an antibiotic used to treat infections caused by multidrug-resistant Gram-negative bacteria as a last-line therapeutic option, to form ion pores in model membranes composed of various phospholipids and lipopolysaccharides was studied. Our data demonstrate that polymyxin B...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598075/ https://www.ncbi.nlm.nih.gov/pubmed/36290103 http://dx.doi.org/10.3390/antibiotics11101445 |