Antioxidative Self-Assembling Nanoparticles Attenuate the Development of Steatohepatitis and Inhibit Hepatocarcinogenesis in Mice

Oxidative stress (OS) contributes to nonalcoholic steatohepatitis (NASH) and hepatocarcinogenesis. We investigated whether antioxidative self-assembling nanoparticles (SMAPo(TN)) could reduce the development of NASH and hepatocellular carcinoma (HCC) in p62/Sqstm1 and Nrf2 double knockout (DKO) mice...

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Detalles Bibliográficos
Autores principales: Watahiki, Takahisa, Okada, Kosuke, Miura, Ikuru, To, Keii, Tanaka, Seiya, Warabi, Eiji, Kanno, Naomi, Yamagata, Kenji, Gotoh, Naohiro, Suzuki, Hideo, Ariizumi, Shunichi, Tsuchiya, Kiichiro, Nagasaki, Yukio, Shoda, Junichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598142/
https://www.ncbi.nlm.nih.gov/pubmed/36290662
http://dx.doi.org/10.3390/antiox11101939

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598142/
https://www.ncbi.nlm.nih.gov/pubmed/36290662
http://dx.doi.org/10.3390/antiox11101939

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