Improvement of the Antibacterial Activity of Phage Lysin-Derived Peptide P87 through Maximization of Physicochemical Properties and Assessment of Its Therapeutic Potential

Phage lysins are a promising alternative to common antibiotic chemotherapy. However, they have been regarded as less effective against Gram-negative pathogens unless engineered, e.g., by fusing them to antimicrobial peptides (AMPs). AMPs themselves pose an alternative to antibiotics. In this work, A...

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Detalles Bibliográficos
Autores principales: Vázquez, Roberto, Doménech-Sánchez, Antonio, Ruiz, Susana, Sempere, Julio, Yuste, Jose, Albertí, Sebastián, García, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598152/
https://www.ncbi.nlm.nih.gov/pubmed/36290106
http://dx.doi.org/10.3390/antibiotics11101448

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598152/
https://www.ncbi.nlm.nih.gov/pubmed/36290106
http://dx.doi.org/10.3390/antibiotics11101448

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