Cargando…

HDAC1 in the Ovarian Granulosa Cells of Tan Sheep Improves Cumulus Cell Expansion and Oocyte Maturation Independently of the EGF-like Growth Factors

SIMPLE SUMMARY: This study aimed to explore the possible role of histone deacetylase 1 (HDAC1), an epigenetic modifying enzyme, in the improvement of oocyte maturation recovered from the Tan sheep of China. We supplemented a specific inhibitor of HDAC1 to in vitro-cultured cumulus oocyte complexes (...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Yaxiu, Fan, Shanshan, Liu, Yujun, Shi, Jiaqi, Xie, Xianguo, Wang, Xiangyan, Wang, Chao, Liu, Xinfeng, Xia, Guoliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9598242/
https://www.ncbi.nlm.nih.gov/pubmed/36290368
http://dx.doi.org/10.3390/biology11101464